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By Steve Holland, Roberta Rampton and David Morgan WASHINGTON (Reuters) - Kathleen Sebelius' departure as President Barack Obama's health secretary signals a new chapter in the White House's efforts to defend Obama's signature healthcare law and help Senate Democrats who face tough battles for re-election in conservative states this fall. In the tightly orchestrated transition that included Sebelius' resignation late Thursday and Obama's quick appointment of well-regarded budget director Sylvia Mathews Burwell as Sebelius' replacement, the political calculus was clear: Having stood by Sebelius during a painful few months when Obamacare's rollout was marred by a balky enrollment web site, stinging criticism from Republicans and falling popularity ratings for Obama, the White House saw a chance to reset the national conversation over Obamacare amid good news, and with a new face in charge of the program.
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