Brad Pitt was hilarious in this movie, and McDermot and Clooney acted their roles well.
But the plot was ... well, it could have been done a lot better. The basic premise was interesting (how they are all intermingling without knowing it) but beyond that left me sitting there going "huh?" through most of the movie.
I paid $3.50 at the cheapy theater to see it and was very glad I didn't pay full price.